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Peer-Reviewed Publicaitons

14. A stereoselective photoinduced cycloisomerization inspired by ophiobolin A

JA Law, DP Callen, EL Paola, G Gomes and JH Frederich*

Org. Lett, 2022, ASAP. DOI: 10.1021/acs.orglett.2c02272

Preprint: 10.26434/chemrxiv-2022-wjsd9

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13. Programmed polyene cyclization enabled by chromophore disruption

MM Solans, VS Basistyi, JA Law, NM Bartfield and JH Frederich*

J. Am. Chem. Soc. 2022, 144, 6193–6199. DOI: 10.1021/jacs/2c02144

Preprint: 10.26434/chemrxiv-2022-npd5r-v2

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12. Pyridazine N-oxides as photoactivatable surrogates for reactive oxygen species

VS Basistyi and JH Frederich*

Org. Lett. 2022, 24, 1907–1912. DOI: 10.1021/acs.orglett.2c00227

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11. Site-specific alkene hydromethylation via protonolysis of titanacyclobutanes

JA Law, NM Bartfield, and JH Frederich*

Angew. Chem., Int. Ed. 2021, 60, 14360–14364. DOI: 10.1002/anie.202103278

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9. Analysis of interactions stabilized by fusicoccin A reveals an expanded suite of potential 14-3-3 binding partners

A Sengupta, J Liriano, BG Miller and JH Frederich*

ACS Chem. Bio. 2020, 15, 305–310. DOI: 10.1021/acschembio.9b00795

8. A photoinduced cascade for the synthesis of 1H-indole-2-acetamide derivatives

M Borger, DP Callen and JH Frederich*

Asian J. Org. Chem. 2019, 8, 1111–1114. DOI: 10.1002/ajoc.201900201

Special Issue – Advances in Heterocyclic Chemistry

10. Probing the 14-3-3 isoform-specificity profile of protein-protein interactions stabilized by fusicoccin A

A Sengupta, J Liriano, EA Bienkiewicz, BG Miller and JH Frederich*

ACS Omega 2020, 5, 25029–25035. DOI: 10.1021/acsomega.0c01454

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7. Pyridazine N-oxides as precursors to 2-aminofurans: Scope and limitations in complexity building cascade reactions

M Borger and JH Frederich*

Org. Lett. 2019, 21, 2397–2401. DOI: 10.1021/acs.orglett.9b00682

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6. Modular access to functionalized 5-8-5 ring systems via a photoinduced cycloisomerization reaction 

AE Salvati, JA Law, J Liriano and JH Frederich*

Chem. Sci. 2018, 9, 5389–5393. DOI: 10.1039/c8sc00999f

This work was highlighted in Chemistry World

5. Synthesis of nitrogen heterocycles via photochemical ring opening of pyridazine N-oxides

M Portillo, MA Maxwell and JH Frederich*

Org. Lett. 2016, 18, 5142–5145. DOI: 10.1021/acs.orglett.6b02562.

Prior to independent career

4. Tailored fragments of roseophilin selectively antagonize Mcl-1 in vitro

    JD Bracken, AD Carlson, JH Frederich, M Nguyen, GS Shore and PG Harran*

    Tetrahedron Lett. 2015, 56, 3612–3616.

    Memorial Symposium-in-Print for Harry Wasserman

3. Modular access to complex prodiginines: Total synthesis of (+)-roseophilin via its 2-azafulvene prototropisomer

    JH Frederich and PG Harran*

    J. Am. Chem. Soc. 2013, 135, 3788–3791.

2. Substituted 2,2'-bipyrroles and pyrrolylfurans via intermediate isoxazolylpyrroles

    JH Frederich, JK Matsui, RO Chang, and PG Harran*

    Tetrahedron Lett. 2013, 54, 2645–2647.

1. Palladacyclic imidazoline-naphthalene complexes: Synthesis and catalytic performance in Pd(II)-catalyzed enantioselective reactions of allylic                     trichloroacetimidates

    JS Cannon, JH Frederich and LE Overman*

    J. Org. Chem. 2012, 77, 1939–1951.

Patents

2. Fusicoccane derivatives and methods

    James H. Frederich and Anna E. Salvati

    62/492,632 Provisional Patent Application, Filed 5/3/2017

1. Mcl-1 antagonists

    Patrick G. Harran, James H. Frederich, Gordon S. Shore and Mai Nguyen

    WO2015134539. Filed March 3rd, 2015

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