Publications

6. Probing the 14-3-3 isoform-specificity profile of interactions stabilized by fusicoccin A

Ananya Sengupta, Josue Liriano, Ewa A. Sienkiewicz, Brian G. Miller and James H. Frederich

Submitted. DOI: 10.26434/chemrxiv.12052869

5. Analysis of interactions stabilized by fusicoccin A reveals an expanded suite of potential 14-3-3 binding partners

Ananya Sengupta, Josue Liriano, Brian G. Miller and James H. Frederich

ACS Chem. Bio. 2020, 15, 305–310. DOI: 10.1021/acschembio.9b00795

4. A photoinduced cascade for the synthesis of 1H-indole-2-acetamide derivatives

Maribel Borger, Daniel P. Callen and James H. Frederich

Asian J. Org. Chem. 2019, 8, 1111–1114. DOI: 10.1002/ajoc.201900201

Special Issue – Heterocyclic Chemistry

3. Pyridazine N-oxides as precursors to 2-aminofurans: Scope and limitations in complexity building cascade reactions

Maribel Borger and James H. Frederich

Org. Lett. 2019, 21, 2397–2401DOI: 10.1021/acs.orglett.9b00682

2. Modular access to functionalized 5-8-5 ring systems via a photoinduced cycloisomerization reaction 

Anna E. Salvati, James A. Law, Josue Liriano and James H. Frederich

Chem. Sci. 20189, 5389–5393. DOI: 10.1039/c8sc00999f

This work was highlighted in Chemistry World

1. Synthesis of nitrogen heterocycles via photochemical ring opening of pyridazine N-oxides

Maribel Portillo, Michael A. Maxwell and James H. Frederich

Org. Lett. 201618, 5142–5145. DOI: 10.1021/acs.orglett.6b02562.

Prior to independent career

4. Tailored fragments of roseophilin selectively antagonize Mcl-1 in vitro

    Jack D. Bracken, Andrew D. Carlson, James H. Frederich, Mai Nguyen, Gordon S. Shore and Patrick G. Harran

    Tetrahedron Lett. 201556, 3612–3616.

    Memorial Symposium-in-Print for Harry Wasserman

3. Modular access to complex prodiginines: Total synthesis of (+)-roseophilin via its 2-azafulvene prototropisomer

    James H. Frederich and Patrick G. Harran

    J. Am. Chem. Soc. 2013135, 3788–3791.

2. Substituted 2,2'-bipyrroles and pyrrolylfurans via intermediate isoxazolylpyrroles

    James H. Frederich, Jennifer K. Matsui, Randy O. Chang and Patrick G. Harran

    Tetrahedron Lett. 201354, 2645–2647.

1. Palladacyclic imidazoline-naphthalene complexes: Synthesis and catalytic performance in Pd(II)-catalyzed enantioselective reactions of allylic                     trichloroacetimidates

    Jeffrey S. Cannon, James H. Frederich and Larry E. Overman

    J. Org. Chem. 2012, 77, 1939–1951.

Patents

2. Fusicoccane derivatives and methods

    James H. Frederich and Anna E. Salvati

    62/492,632 Provisional Patent Application, Filed 5/3/2017

1. Mcl-1 antagonists

    Patrick G. Harran, James H. Frederich, Gordon S. Shore and Mai Nguyen

    WO2015134539. Filed March 3rd, 2015