The Frederich Laboratory
Complex Molecule Synthesis & Molecular Pharmacology

email: jfrederich@fsu.edu
phone: 503-869-1287 (cell)
James H. Frederich, Ph.D.
Werner Herz Associate Professor
Jim received his B.S. in Biochemistry at the University of Oregon where he carried out undergraduate research under the supervision of Mike Haley. In 2005, he moved to Southern California for his Ph.D. studies with Larry Overman at UC Irvine. His thesis work involved enantioselective Pd-catalyzed reactions of allylic trichloroacetimidates. After obtaining his Ph.D. in 2011, he moved to UCLA where he was supported as an American Cancer Society Postdoctoral Fellow in the laboratory of Patrick Harran. His postdoctoral research focused on the total synthesis of prodiginine natural products and related efforts to optimize their function as antagonists of protein-protein interactions (PPIs) that gate mitochondrial apoptosis.
Jim joined the faculty at Florida State University in July 2014. His research group is broadly interested in leveraging synthetic organic chemistry to address problems at the interface of chemistry, biology, and medicine.
Academic Experience
2024–present Werner Herz Associate Professor
Department of Chemistry & Biochemistry, Florida State University
2022–2024 Associate Professor
Department of Chemistry & Biochemistry, Florida State University
2014–2022 Assistant Professor
Department of Chemistry & Biochemistry, Florida State University
2011–2014 American Cancer Society Postdoctoral Fellow
Department of Chemistry & Biochemistry, UCLA
2005–2011 UC Irvine
Ph.D in Chemistry
2001–2005 University of Oregon
B.S. in Biochemistry
Professional Experience
2025–present Scientific Advisor
Permanence Bio, San Francisco, CA
2025–present Director of Chemistry
Cryton Biosciences, Minneapolis, MN
2023–present co-Founder and CSO
Cypris Therapeutics, Syracuse, NY
2023–present Head of Medicinal Chemistry
LentoBio, Syracuse, NY
Honors & Awards
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Associate Member, Academy of Science, Engineering, and Medicine of Florida, 2026
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Inaugural Recipient of the Werner Herz Endowment, 2024
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FSU Developing Scholar Award, 2024
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FSU Foundational Course Excellence Award, 2023
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FSU Honors Thesis Mentor Award, 2022
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First Year Assistant Professor Award, FSU 2015
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Amgen Award for Postdoctoral Research, 2013
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Molecular Biology Institute (MBI) Certificate of Excellence, UCLA 2013
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Chancellor's Award Nominee for Excellence in Postdoctoral Research, UCLA 2013
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American Cancer Society Postdoctoral Fellow, 2013–2014
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UC Irvine Dissertation Fellowship, 2011
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Organic Chemistry Achievement Award, UO 2005
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Oregon Presidential Scholarship, 2001–2005
